Sunday, April 12, 2015

Part 1- Chapters 1- 9 Question 38

What is the fatality rate in Ebola Sudan strain (subtype) and how does it compare to the Marburg strain and to the bubonic plague in medieval Europe?

5 comments:

  1. The fatality rate in Ebola Sudan was 50%; half of those who became infected died quickly while the others survived. This death rate was exactly the same as the Bubonic plague during the medieval times. The Ebola Sudan virus is “twice as lethal” (Preston 99) as the Marburg virus. So two in four of those infected with Ebola Sudan would die while only one in four of those infected with the Marburg virus would die. Ebola Sudan is the second worst of the three filovirus sisters. The Marburg virus attacks the “internal organs, connective tissue, intestines, and skin” (Preston 38). The Marburg virus also made those infected slightly aggressive or negative. Ebola Sudan would give one the typical symptoms of Ebola which includes: fever, severe headaches, fatigue, diarrhea, vomiting, and unexplained hemorrhage” (Centers for Disease Control and Prevention 2015).The Bubonic plague was a bacterial infection that affected the lymph nodes and was transmitted through fleas of small rodents. Symptoms including “chills, fever, headache, seizures, and lymph swelling” (MedlinePlus 2015) occurred 2 to 5 days after infection. The bubonic plague and the two other are distinctly different since the plague was a bacterial infection while both Marburg and Ebola Sudan are viral infections. The bubonic plague can be treated with antibiotic while Ebola doesn't have a cure yet.

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    1. Hi Cassandra, what is the most lethal Ebola virus? Also, how many strains are there and from where do they originate?

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    2. In addition to Cassandra’s response, both the Ebola virus and the Marburg virus are known as filoviruses, which “belong to the family Filoviridae” (“Ebola Hemorrhagic Fever”). To be more specific filoviruses are “enveloped, filamentous viruses with a single-stranded RNA genome” (“Ebola Hemorrhagic Fever”). Today, there are five different types of the Ebola virus, including the Ebola Sudan virus—this virus was discovered south of Sudan on June 1976. This virus causes Ebola virus (EBOV) disease in humans and non-human primates (example, apes). To clarify, EBOV comes from the humid rain forests in Central and western Africa, including the Philippines. The Ebola Sudan virus, the Marburg virus, and the bubonic plague were transmitted through human to human contact, specifically blood transmission.

      Ebola Hemorrhagic Fever. (2013, June 19). Retrieved April 20, 2015, from http://www.cdc.gov/ncidod/dvrd/spb/outbreaks/qaEbolaRestonPhilippines.htm

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  2. The most lethal strain of Ebola is Ebola Zaire. Nine out of ten infected with Ebola Zaire will die. Ebola Zaire is considered to be a “slate wiper” (Preston 38) in humans. As of right now, there are five strains of Ebola: Ebola Zaire, Ebola Sudan, Tai Forest ebolavirus, Bundibugyo ebolavirus, and Reston ebolavirus. The first four affect human except Reston ebolavirus, which only affect primates (Centers for Disease Control and Prevention 2015). Each and every strain of Ebola is named after the place where it originated. The strains are called Ebola because the first strain originated from the Ebola River in the Democratic Republic of Congo. The original host of the virus isn’t known but many researchers believe that bats are most likely the host.

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